Description

1-(3-Bromophenyl)-Cyclobutanecarbonitrile is a versatile and high-purity organic building block, specifically a substituted cyclobutane derivative, essential for advanced synthetic chemistry. Its core value lies in providing a rigid, functionalized scaffold for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bromophenyl and nitrile functionalities for bioactivity.
• Ligand & Catalyst Development: Serves as a sophisticated ligand precursor in organometallic chemistry and asymmetric catalysis for fine chemical production.
• Material Science: Employed in the synthesis of specialty polymers and liquid crystals where the cyclobutane ring contributes to specific thermal and mechanical properties.
• Chemical Biology Probes: Utilized as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the biotechnology and specialty chemical industries.

Basic Information

Product Name	1-(3-Bromophenyl)-Cyclobutanecarbonitrile
CAS No.	29786-38-7
Molecular Formula	C11H10BrN
Molecular Weight	236.11 g/mol
Synonyms	3-Bromophenylcyclobutanecarbonitrile; (3-Bromophenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(3-bromophenyl)-; 1-(3-Bromophenyl)cyclobutanecarbonitrile; 3-Bromo-α-cyanocyclobutylbenzene; 1-(m-Bromophenyl)cyclobutanecarbonitrile; m-Bromophenylcyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)-Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.