Description

1-Fluoro-3-(2-Phenylethynyl)Benzene is a specialized fluorinated aromatic alkyne building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a fluorine substituent with a rigid, linear phenylethynyl group, enabling precise structural modifications in target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex bioactive molecules, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that benefit from the stability and lipophilicity imparted by the fluorine atom.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in Sonogashira, Suzuki, and other cross-coupling reactions to introduce the 3-(phenylethynyl)phenyl moiety into more complex systems.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on molecular conformation, electronic properties, and reactivity.

Basic Information

Product Name	1-Fluoro-3-(2-Phenylethynyl)Benzene
CAS No.	29778-28-7
Molecular Formula	C14H9F
Molecular Weight	196.22 g/mol
Synonyms	3-(Phenylethynyl)fluorobenzene; 1-Fluoro-3-(phenylethynyl)benzene; 3-Fluoro-1-(phenylethynyl)benzene; m-(Phenylethynyl)fluorobenzene; 3-Fluorodiphenylacetylene; 1-Ethynyl-3-fluorobenzene (phenyl derivative); [1,1'-Biphenyl]-3-fluoro-4-ethynyl (alternative naming)
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-(2-Phenylethynyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.