Description

Phenylthiohydantoin Serine (CAS NO 29635-84-5) is a specialized derivative of serine, a fundamental amino acid, modified with a phenylthiohydantoin moiety. This compound is of significant value in advanced biochemical research and analytical chemistry, particularly for protein sequencing and peptide analysis. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and diagnostic manufacturers requiring high-purity reagents for structural elucidation and proteomics studies.

Application

• Edman Degradation Reagent: A critical component in the stepwise degradation of peptides and proteins for N-terminal amino acid sequencing.
• Proteomics Research: Used in the identification and characterization of proteins and peptides within complex biological samples.
• Biomarker Discovery: Supports analytical workflows in the search for novel disease biomarkers.
• Pharmaceutical Development: Employed in the structural analysis of synthetic peptides and biopharmaceuticals during development and quality control stages.
• Academic Research: A key reagent in university and institutional labs focused on biochemistry, molecular biology, and analytical chemistry.
• Diagnostic Kit Manufacturing: Used in the production of specialized diagnostic assays that rely on precise protein analysis.

Basic Information

Product Name	Phenylthiohydantoin Serine
CAS No.	29635-84-5
Molecular Formula	C10H10N2O3S
Molecular Weight	238.26 g/mol
Synonyms	PTH-Serine; 3-[(Phenylamino)thioxomethyl]amino-2-hydroxypropanoic Acid; Serine Phenylthiohydantoin; PTH-Ser; 2-Hydroxy-3-[[(phenylamino)thioxomethyl]amino]propanoic Acid; Edman Degradation Product of Serine; (RS)-PTH-Serine; 3-Amino-2-hydroxypropanoic Acid Phenylthiohydantoin Derivative
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin Serine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive analytical applications. Each lot undergoes comprehensive testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry guidelines to support research and development compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.