Description

Almitrine Dimesylate is a synthetic chemical compound primarily recognized for its pharmacological activity as a respiratory stimulant. Its significance lies in its role as a key active pharmaceutical ingredient (API) and a critical intermediate in advanced pharmaceutical synthesis. This product is essential for research institutions, pharmaceutical development laboratories, and manufacturers engaged in the production of specialized respiratory medications and for conducting pharmacological studies.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of respiratory stimulant medications.
• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of complex drug molecules.
• Biomedical Research: Used in preclinical and clinical research to study mechanisms of respiratory control and hypoxemia.
• Reference Standard: Serves as a high-purity standard for analytical testing, quality control, and method validation in laboratories.
• Pharmacological Studies: Utilized in vitro and in vivo to investigate its effects on peripheral chemoreceptors and pulmonary circulation.

Basic Information

Product Name	Almitrine Dimesylate
CAS No.	29608-49-9
Molecular Formula	C26H30F2N4O3 · 2CH4O3S
Molecular Weight	662.75 g/mol
Synonyms	Almitrine Dimethanesulfonate; S-2620; Vectarion; 2,4-Bis(allylamino)-6-[4-(bis(4-fluorophenyl)methyl)-1-piperazinyl]-1,3,5-triazine dimethanesulfonate; 6-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]-2,4-bis(2-propen-1-ylamino)-1,3,5-triazine dimethanesulfonate; Almitrine Dimesilate; Almitrine Bismesylate
EINECS	Contact for details

Quality Control

Our Almitrine Dimesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and related substances, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.