Description

Pht-Ile-Oh CAS NO 29588-88-3 is a high-purity, protected amino acid derivative, specifically N-Phthaloyl-L-isoleucine, widely utilized in advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled construction of complex peptides and other bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected isoleucine residue.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Proteomics Research: Valuable tool for studying protein structure-function relationships and enzyme specificity.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	Pht-Ile-Oh
CAS No.	29588-88-3
Molecular Formula	C14H15NO4
Molecular Weight	261.27 g/mol
Synonyms	N-Phthaloyl-L-isoleucine; (2S,3S)-2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3-methylpentanoic acid; Phth-Ile-OH; L-Isoleucine, N-phthaloyl-; N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-L-isoleucine; Phthalimidoisoleucine; N-Phthalimido-L-isoleucine; 29588-88-3
EINECS	Contact for details

Quality Control

Our Pht-Ile-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with the standards required for GMP and ISO-guided production environments, supporting your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.