Description

Moracizine Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) with significant importance in cardiovascular research and development. Its primary value lies in its role as a Class I antiarrhythmic agent, specifically studied for its effects on cardiac sodium channels. This compound is essential for pharmaceutical manufacturers, research institutions, and chemical suppliers engaged in the synthesis of novel therapeutic agents or reference standards for cardiac conditions.

Application

• Pharmaceutical API Synthesis: Primary use as an active pharmaceutical ingredient in the formulation of antiarrhythmic medications.
• Cardiovascular Research: Critical reference standard and biochemical tool in preclinical and clinical studies investigating cardiac electrophysiology and arrhythmia mechanisms.
• Chemical Intermediate: Serves as a key building block in the multi-step synthesis of more complex pharmaceutical compounds and analogs.
• Analytical Standard: Used as a high-purity calibration standard in HPLC, LC-MS, and other analytical methods for quality control and pharmacokinetic studies.
• Academic & Institutional Research: Employed in university and hospital laboratories for pharmacological profiling and toxicology assessments.

Basic Information

Product Name	Moracizine Hydrochloride
CAS No.	29560-58-5
Molecular Formula	C22H25N3O3 • HCl
Molecular Weight	415.91 g/mol
Synonyms	Ethmozine Hydrochloride; Moracizine HCl; Moratsizin; EN-313; Ethmozin; Aetmozine; Moricizine Hydrochloride; 10-(3-Morpholinopropionyl)phenothiazine Hydrochloride
EINECS	Contact for details

Quality Control

Our Moracizine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A detailed Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and other critical parameters is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmospheres.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.