Description

n-Acryloyl-2-Methylalanine is a specialized acrylic acid derivative featuring both a polymerizable acryloyl group and a carboxylic acid functionality. This unique bifunctional structure makes it a valuable monomer and intermediate for synthesizing advanced polymers with tailored properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, specialty polymer, and advanced materials sectors for creating functionalized copolymers, hydrogels, and drug delivery systems.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring carboxylic acid functionality for conjugation.
• Functional Monomer for Hydrogels: Used in the copolymerization to create pH-responsive or biodegradable hydrogels for biomedical applications, including wound dressings and controlled release matrices.
• Advanced Polymer Synthesis: Serves as a comonomer to introduce carboxylic acid groups into acrylic and methacrylic polymer backbones, enhancing adhesion, dyeability, or reactivity.
• Crosslinking Agent: Utilized in formulations for coatings, adhesives, and sealants where its dual functionality can promote crosslinking, improving film hardness and chemical resistance.
• Bioconjugation and Protein Modification: The acryloyl group allows for Michael addition reactions with thiols, making it useful for modifying peptides, proteins, or other biomolecules.
• Dental and Biomedical Materials: Incorporated into resin compositions for dental restoratives or bone cements to modify mechanical properties and biocompatibility.

Basic Information

Item	Details
Product Name	n-Acryloyl-2-Methylalanine
CAS No.	29513-50-6
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	2-Methyl-2-acrylamidopropanoic acid; Acryloyl-2-methylalanine; N-Acryloyl-2-methylalanine; 2-Acrylamido-2-methylpropionic acid (common misnomer for related compound); N-(1-Carboxy-1-methylethyl)acrylamide; Acrylic acid, 2-(1-carboxy-1-methylethylamino)-2-oxoethyl ester (alternative representation); AMA (abbreviation).
EINECS	Contact for details

Quality Control

Our n-Acryloyl-2-Methylalanine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.