Description

2(1H)-Naphthalenone, 3-Fluoro-3,4,4A-α-,5,6,7,8,8A-Bta--Octahydro- (8Ci) is a specialized fluorinated octahydronaphthalenone derivative, serving as a valuable chiral building block and synthetic intermediate in advanced organic chemistry. Its unique stereochemistry and fluorine substitution make it a critical precursor for developing novel pharmaceutical compounds and agrochemicals with enhanced biological activity and metabolic stability. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create complex, stereodefined molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used as a building block for developing new-generation herbicides, fungicides, and insecticides where the fluorine atom and specific stereochemistry can improve efficacy and environmental profile.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts for enantioselective synthesis due to its rigid, polycyclic framework.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers and liquid crystals with specific optical or electronic properties.
• Academic & Contract Research: Serves as a valuable reference standard and starting material in academic laboratories and CROs (Contract Research Organizations) for methodological development and complex molecule synthesis.

Basic Information

Item	Details
Product Name	2(1H)-Naphthalenone, 3-Fluoro-3,4,4A-α-,5,6,7,8,8A-Bta--Octahydro- (8Ci)
CAS No.	29293-35-4
Molecular Formula	C₁₀H₁₃FO
Molecular Weight	168.21 g/mol
Synonyms	3-Fluoro-3,4,4aα,5,6,7,8,8aβ-octahydro-2(1H)-naphthalenone; 3-Fluoro-3,4,4a,5,6,7,8,8a-octahydro-2H-naphthalen-1-one; 3-Fluoro-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1(2H)-one; 3-Fluoro-octahydro-2(1H)-naphthalenone; 3-Fluoro-perhydronaphthalen-1-one; Fluorinated octahydronaphthalenone; 29293-35-4 (CAS)
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Naphthalenone, 3-Fluoro-3,4,4A-α-,5,6,7,8,8A-Bta--Octahydro- (8Ci) adheres to stringent in-process controls and final release specifications to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, potency, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture uptake. Observe all local regulations for the storage of chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.