Description

25 26-Dihydroxyvitamin D3* is a biologically active metabolite of Vitamin D3, playing a crucial role in calcium and phosphate homeostasis. This high-purity compound is essential for advanced research and development in endocrinology and metabolic disease studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-end biochemical reagents and reference standards.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the development of novel Vitamin D analogs and therapies for osteoporosis, psoriasis, and secondary hyperparathyroidism.
• Biochemical Research: Used as a critical tool to study Vitamin D metabolism, receptor binding, and signaling pathways in cellular and molecular biology.
• Reference Standard Manufacturing: Serves as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical and nutritional analysis.
• Diagnostic Kit Production: Employed in the development and calibration of immunoassays and LC-MS/MS kits for the precise quantification of Vitamin D metabolites in clinical samples.
• Academic Studies: Fundamental for investigating the non-classical actions of Vitamin D, including its effects on immune modulation, cell differentiation, and proliferation.

Basic Information

Product Name	25 26-Dihydroxyvitamin D3*
CAS No.	29261-12-9
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64 g/mol
Synonyms	25,26-Dihydroxycholecalciferol; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3β,25,26-triol; 25,26-Dihydroxyvitamin D₃; 25,26-(OH)₂D₃; 25,26-Dihydroxy-D3; Vitamin D3 metabolite 25,26-diol
EINECS	Contact for details

Quality Control

Our 25 26-Dihydroxyvitamin D3* is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.