Description

2,2,2-Trifluoro-n-[2-Oxo-2-(p-Nitrophenyl)Ethyl]Acetamide is a specialized fluorinated acetamide derivative with a nitrophenyl ketone moiety, making it a valuable synthetic intermediate. This compound is significant for its role in constructing complex molecules, particularly in advanced pharmaceutical and agrochemical research where the trifluoromethyl and nitro groups confer specific electronic and biological properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, or insecticides where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing the 2,2,2-trifluoroacetamide and p-nitrophenylacetyl groups into more complex molecular architectures.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced materials with unique optical or electronic properties.
• Chemical Biology Probe Development: Utilized in creating labeled compounds or activity-based probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2,2,2-Trifluoro-n-[2-Oxo-2-(p-Nitrophenyl)Ethyl]Acetamide
CAS No.	29205-55-8
Molecular Formula	C10H7F3N2O4
Molecular Weight	276.17 g/mol
Synonyms	N-(2,2,2-Trifluoroacetyl)-2-amino-4'-nitroacetophenone; 2,2,2-Trifluoro-N-[2-(4-nitrophenyl)-2-oxoethyl]acetamide; 2-Amino-4'-nitroacetophenone Trifluoroacetamide; 4'-Nitro-2-trifluoroacetamidoacetophenone; N-(4-Nitrophenacyl)trifluoroacetamide; TFAA derivative of 2-amino-4'-nitroacetophenone; 29205-55-8; p-Nitrophenacyl trifluoroacetamide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-[2-Oxo-2-(p-Nitrophenyl)Ethyl]Acetamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.