Description

[3-(n-Butylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid is a high-purity, tri-iodinated organic compound primarily used as a key intermediate in the synthesis of advanced X-ray contrast media. Its value lies in providing a critical, high-quality building block for pharmaceutical manufacturers, ensuring the reliability and efficacy of the final diagnostic agents. This product is essential for R&D and production within the pharmaceutical and fine chemical industries, particularly for companies developing non-ionic, low-osmolar contrast media.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of iodinated X-ray contrast agents like iopamidol, iohexol, and ioversol.
• Contrast Media Research: Serves as a foundational compound in R&D for developing new generations of safer, more effective radiographic contrast media.
• Fine Chemical Synthesis: Used in specialized organic synthesis to introduce the tri-iodophenyl moiety into complex molecules for diagnostic applications.
• GMP Manufacturing: Supplied as a qualified starting material for cGMP (Current Good Manufacturing Practice) production processes in regulated pharmaceutical facilities.

Basic Information

Product Name	[3-(n-Butylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid
CAS No.	29193-36-0
Molecular Formula	C14H15I3N2O3
Molecular Weight	647.99 g/mol
Synonyms	3-(N-Butylacetamido)-2,4,6-triiodophenylacetic Acid; 3-(Butylacetamido)-2,4,6-triiodohydrocinnamic Acid; B-28630; Iopamidol Intermediate; Iohexol Intermediate; 2-[3-(Butylacetamido)-2,4,6-triiodophenyl]acetic Acid; NSC 401564; Acetic acid, [3-[(butylamino)carbonyl]-2,4,6-triiodophenyl]-
EINECS	Contact for details

Quality Control

Our [3-(n-Butylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid is manufactured under strict quality systems to meet the exacting standards of pharmaceutical intermediate applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant ICH guidelines and can support customer audits and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.