Description

[3-(n-Benzylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its molecular structure, featuring a triiodinated phenyl ring, is critical for imparting the high radiodensity required in diagnostic imaging agents. This high-purity intermediate is essential for pharmaceutical manufacturers and advanced research facilities developing next-generation non-ionic contrast agents, ensuring product efficacy and regulatory compliance.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of non-ionic, low-osmolar X-ray contrast media such as iopamidol, iohexol, and ioversol.
• Diagnostic Imaging Research: Used in R&D for developing novel contrast agents with improved safety profiles and imaging characteristics.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step manufacturing process of iodinated contrast agent APIs.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in contrast media production.
• Radiopharmaceutical Precursor: Investigated for use in creating compounds for targeted diagnostic imaging.

Basic Information

Product Name	[3-(n-Benzylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid
CAS No.	29193-35-9
Molecular Formula	C17H15I3NO3
Molecular Weight	695.02 g/mol
Synonyms	N-Benzyl-2-[2,4,6-triiodo-3-(acetylamino)phenyl]acetamide; 2-[[3-(Acetylamino)-2,4,6-triiodophenyl]methylamino]-2-oxoethyl]benzene; Benzyl-[3-(acetylamino)-2,4,6-triiodophenyl]acetate Amide; BTA; Contrast Media Intermediate BTA; Iopamidol Intermediate; Iohexol Precursor
EINECS	Contact for details

Quality Control

Our [3-(n-Benzylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance as a pharmaceutical intermediate. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting audits for cGMP, ICH Q7, and other global pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.