Description

[3-(n-Ethylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid is a high-purity, tri-iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its value lies in its precise molecular structure, which is critical for producing safe and effective diagnostic agents with optimal imaging properties. This product is essential for manufacturers in the pharmaceutical and fine chemical industries who require a reliable, high-quality building block for advanced medical formulations.

Application

• Primary Intermediate for X-ray Contrast Media: A crucial building block in the synthesis of non-ionic, low-osmolar contrast agents used in diagnostic imaging.
• Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of final drug substances for computed tomography (CT) and angiography.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for developing new diagnostic compounds.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of specialized iodinated aromatic compounds.

Basic Information

Product Name	[3-(n-Ethylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid
CAS No.	29193-33-7
Molecular Formula	C12H11I3NO3
Molecular Weight	647.94 g/mol
Synonyms	N-Acetyl-N-ethyl-2,4,6-triiodo-5-[(carboxymethyl)amino]-3-aminobenzoic Acid; 5-[Acetyl(ethyl)amino]-2,4,6-triiodo-3-[(carboxymethyl)amino]benzoic Acid; Iopanoic Acid Impurity; Iopanoic Acid Related Compound A; AEI-Tri-I-BA; 2,4,6-Triiodo-3-[(carboxymethyl)amino]-5-[N-ethylacetamido]benzoic Acid
EINECS	Contact for details

Quality Control

Our [3-(n-Ethylacetylamino)-2,4,6-Triiodophenyl]Acetic Acid is manufactured under strict quality management systems. Each batch is tested to ensure it meets exacting standards for purity and identity, suitable for use in pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.