Description

5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 3-Methyl-8-Oxo-7-[(2-Phenylacetyl)Amino]-, (4-Methoxyphenyl)Methyl Ester, (6R,7R)- is a key advanced pharmaceutical intermediate in the synthesis of β-lactam antibiotics. This compound matters for its role as a critical building block in the production of high-purity, potent cephalosporin drugs. Pharmaceutical manufacturers and research organizations need this high-quality intermediate to ensure the efficacy and safety of their final antibiotic formulations.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A crucial intermediate in the multi-step synthesis of cephalosporin-class antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the development and optimization of new β-lactam antibiotic candidates.
• Process Chemistry: Serves as a standardized building block for scaling up antibiotic production under controlled GMP conditions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory testing of cephalosporin APIs.
• Custom Synthesis: A starting material for the preparation of novel cephalosporin derivatives with tailored therapeutic properties.

Basic Information

Item	Details
Product Name	5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 3-Methyl-8-Oxo-7-[(2-Phenylacetyl)Amino]-, (4-Methoxyphenyl)Methyl Ester, (6R,7R)-
CAS No.	29126-11-2
Molecular Formula	C24H24N2O6S
Molecular Weight	468.52 g/mol
Synonyms	7-[(Phenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxybenzyl ester; (6R,7R)-7-Phenylacetamido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxybenzyl ester; Cephalosporin C-3' Ester Intermediate; 4-Methoxybenzyl 7-phenylacetamido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; PMB Ester of 7-ADCA derivative; 7-ADCA PMB Ester (Phenylacetyl); Antibiotic Intermediate 29126-11-2
EINECS	Contact for details

Quality Control

Our 5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 3-Methyl-8-Oxo-7-[(2-Phenylacetyl)Amino]-, (4-Methoxyphenyl)Methyl Ester, (6R,7R)- is produced under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (6R,7R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.