Description

4-Ethynyl-1,1'-Biphenyl is a high-purity organic building block featuring a rigid biphenyl core and a reactive terminal alkyne group. This compound matters as a critical intermediate for constructing advanced materials and pharmaceuticals, enabling the synthesis of complex molecular architectures through cross-coupling and click chemistry. It is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality precursors for their synthetic workflows.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for compounds with extended conjugated systems.
• Material Science Research: Used in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and optoelectronic devices.
• Agrochemical Synthesis: Acts as a building block for creating novel crop protection agents with specific activity profiles.
• Polymer Chemistry: Employed as a monomer or cross-linking agent to create specialty polymers with tailored thermal and mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including Sonogashira and other palladium-catalyzed coupling reactions.
• Ligand Precursor: Can be utilized to synthesize sophisticated ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4-Ethynyl-1,1'-Biphenyl
CAS No.	29079-00-3
Molecular Formula	C14H10
Molecular Weight	178.23 g/mol
Synonyms	4-Ethynylbiphenyl; p-Ethynylbiphenyl; 1-Ethynyl-4-phenylbenzene; 4-Phenylphenylacetylene; Biphenyl-4-ylacetylene; [1,1'-Biphenyl]-4-ylethyne; 4-Acetylenylbiphenyl
EINECS	Contact for details

Quality Control

Our 4-Ethynyl-1,1'-Biphenyl is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with your specified requirements. Our quality commitment supports applications from research to commercial-scale manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.