Description

4,5,6,7-Tetrafluoro-2-Methylindole is a high-value fluorinated indole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique tetrafluoro-substituted aromatic ring system makes it a powerful building block for introducing lipophilicity and metabolic stability into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors, receptor modulators, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and specialty polymers that require fluorinated aromatic components.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: A valuable substrate for further functionalization and cross-coupling reactions in organofluorine chemistry.

Basic Information

Product Name	4,5,6,7-Tetrafluoro-2-Methylindole
CAS No.	29029-70-7
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	2-Methyl-4,5,6,7-tetrafluoro-1H-indole; 4,5,6,7-Tetrafluoro-2-methyl-1H-indole; 1H-Indole, 4,5,6,7-tetrafluoro-2-methyl-; 2-Methyl-4,5,6,7-tetrafluorindole; Tetrafluoro-2-methylindole
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrafluoro-2-Methylindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.