Description

[6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[Amino(4-Hydroxyphenyl)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key chemical intermediate in the synthesis of advanced cephalosporin antibiotics. This compound is critical for pharmaceutical manufacturers seeking to develop and produce potent, broad-spectrum antibacterial agents. It is primarily utilized by the pharmaceutical and fine chemical industries for research, development, and commercial API production.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A crucial building block in the synthesis of third-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new antibacterial compounds.
• Bulk Pharmaceutical Manufacturing: Serves as a high-purity intermediate in the scaled-up production of finished dosage forms.
• Reference Standard: Employed as a certified reference material (CRM) for quality control and analytical method development in QC laboratories.
• Process Chemistry: Integral to developing and optimizing robust, cost-effective synthetic routes for complex β-lactam molecules.

Basic Information

Item	Details
Product Name	[6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[Amino(4-Hydroxyphenyl)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	28894-60-2
Molecular Formula	C20H21N3O7S
Molecular Weight	447.46 g/mol
Synonyms	7-ACA Derivative (4-Hydroxy); 7-[(Amino(4-hydroxyphenyl)acetyl)amino]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin C Intermediate; (6R,7R)-7-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-ADCA derivative; Antibiotic Intermediate
EINECS	Contact for details

Quality Control

Our [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[Amino(4-Hydroxyphenyl)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity pharmaceutical-grade standards, with specifications aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.