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Bis(2-Methylpiperidino)Phenylphosphine CAS NO 28869-93-4
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CAS No.:28869-93-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Bis(2-Methylpiperidino)Phenylphosphine is a specialized organophosphorus compound featuring a central phosphorus atom bonded to a phenyl group and two 2-methylpiperidino substituents. This structure makes it a valuable ligand and catalyst precursor in advanced chemical synthesis, particularly for facilitating challenging cross-coupling and reduction reactions. It is primarily utilized by pharmaceutical intermediates, agrochemical, and specialty chemical manufacturers who require high-purity, performance-driven reagents for their R&D and production processes.
Application
- As a ligand in transition metal catalysis for cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
- As a catalyst precursor in the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
- In asymmetric hydrogenation and other stereoselective transformations.
- For the preparation of organometallic complexes used in material science and polymer chemistry.
- As a key intermediate in the development of novel phosphine-based ligands and catalysts.
- In academic and industrial research exploring new catalytic methodologies.
Basic Information
| Product Name | Bis(2-Methylpiperidino)Phenylphosphine |
| CAS No. | 28869-93-4 |
| Molecular Formula | C18H31N2P |
| Molecular Weight | 306.43 g/mol |
| Synonyms | Phenylbis(2-methyl-1-piperidinyl)phosphine; Phenylbis(2-methylpiperidino)phosphine; Bis(2-methylpiperidino)phenylphosphane; (2-Methylpiperidino)diphenylphosphine (related); Phosphine, phenylbis(2-methyl-1-piperidinyl)-; Ligand for cross-coupling |
| EINECS | Contact for details |
Quality Control
Our Bis(2-Methylpiperidino)Phenylphosphine is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is easily oxidized and moisture-sensitive; avoid exposure to air and humidity.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid or low-melting solid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Purity (GC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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