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Bis(2-Methylpiperidino)Phenylphosphine CAS NO 28869-93-4


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CAS No.:28869-93-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis(2-Methylpiperidino)Phenylphosphine is a specialized organophosphorus compound featuring a central phosphorus atom bonded to a phenyl group and two 2-methylpiperidino substituents. This structure makes it a valuable ligand and catalyst precursor in advanced chemical synthesis, particularly for facilitating challenging cross-coupling and reduction reactions. It is primarily utilized by pharmaceutical intermediates, agrochemical, and specialty chemical manufacturers who require high-purity, performance-driven reagents for their R&D and production processes.

Application

  • As a ligand in transition metal catalysis for cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
  • As a catalyst precursor in the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
  • In asymmetric hydrogenation and other stereoselective transformations.
  • For the preparation of organometallic complexes used in material science and polymer chemistry.
  • As a key intermediate in the development of novel phosphine-based ligands and catalysts.
  • In academic and industrial research exploring new catalytic methodologies.

Basic Information

Product Name Bis(2-Methylpiperidino)Phenylphosphine
CAS No. 28869-93-4
Molecular Formula C18H31N2P
Molecular Weight 306.43 g/mol
Synonyms Phenylbis(2-methyl-1-piperidinyl)phosphine; Phenylbis(2-methylpiperidino)phosphine; Bis(2-methylpiperidino)phenylphosphane; (2-Methylpiperidino)diphenylphosphine (related); Phosphine, phenylbis(2-methyl-1-piperidinyl)-; Ligand for cross-coupling
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Quality Control

Our Bis(2-Methylpiperidino)Phenylphosphine is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is easily oxidized and moisture-sensitive; avoid exposure to air and humidity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or low-melting solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Purity (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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