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(4-Methylphenyl)-Bis(1-Piperidyl)Phosphane CAS NO 28869-92-3


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CAS No.:28869-92-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(4-Methylphenyl)-Bis(1-Piperidyl)Phosphane is a specialized organophosphorus compound featuring a phosphine core substituted with a tolyl group and two piperidine rings. This structure makes it a valuable ligand precursor and chemical intermediate in advanced synthetic chemistry, particularly for catalysis and materials science. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and academic research institutions engaged in developing novel catalytic processes and fine chemicals.

Application

  • Catalyst Ligand in Cross-Coupling Reactions: Serves as a precursor for generating palladium and other transition metal catalysts used in C-C and C-N bond-forming reactions (e.g., Suzuki, Heck, Buchwald-Hartwig couplings).
  • Intermediate for Specialty Chemicals: Used in the synthesis of complex phosphine ligands with tailored steric and electronic properties for asymmetric catalysis.
  • Pharmaceutical Research & Development: Employed as a key building block in the discovery and process development of new active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Acts as an intermediate in the creation of novel crop protection agents and plant growth regulators.
  • Materials Science Research: Investigated for the development of novel polymeric materials, metal-organic frameworks (MOFs), and advanced coatings.
  • Academic & Industrial R&D: A critical reagent for methodological studies in organometallic chemistry and new reaction pathway exploration.

Basic Information

Item Detail
Product Name (4-Methylphenyl)-Bis(1-Piperidyl)Phosphane
CAS No. 28869-92-3
Molecular Formula C₁₇H₂₇N₂P
Molecular Weight 290.39 g/mol
Synonyms Bis(1-piperidyl)(p-tolyl)phosphine; (p-Tolyl)bis(piperidino)phosphine; 4-Methylphenyl-bis(piperidin-1-yl)phosphane; Tolylbis(piperidino)phosphine; 1,1'-(4-Methylphenylphosphanediyl)dipiperidine; Phosphine, [4-methylphenyl]bis-1-piperidinyl-; Phosphine, bis(1-piperidinyl)(4-methylphenyl)-
EINECS Contact for details

Quality Control

Our (4-Methylphenyl)-Bis(1-Piperidyl)Phosphane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided. Keep away from strong oxidizers.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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