Description

(20S)-Pregnane-3Alpha,20-Diol is a high-purity steroid derivative and a key intermediate in organic synthesis. This compound is valued for its defined stereochemistry and structural framework, which is crucial for the development of specialized pharmaceutical and research compounds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in steroid chemistry, hormone research, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and endocrine research.
• Steroid Chemistry Development: Serves as a starting material or intermediate for creating novel steroid analogs with potential therapeutic applications.
• Analytical Standard: Employed as a high-purity standard in chromatographic analysis (HPLC, GC) for quality control and method validation.
• Academic & Industrial R&D: Facilitates exploratory synthesis in university and corporate laboratories for drug discovery programs.

Basic Information

Product Name	(20S)-Pregnane-3Alpha,20-Diol
CAS No.	28818-70-4
Molecular Formula	C21H36O2
Molecular Weight	320.51 g/mol
Synonyms	(20S)-Pregnane-3α,20-diol; 3α,20-Dihydroxy-5β-pregnane; 5β-Pregnane-3α,20α-diol; 20α-Hydroxy-5β-pregnan-3α-ol; 3α,20α-Dihydroxy-5β-pregnane; 5β-Pregnan-3α,20α-diol; Pregnanediol (specific isomer); Allopregnanediol (specific isomer)
EINECS	Contact for details

Quality Control

Our (20S)-Pregnane-3Alpha,20-Diol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.