Description

5α-Cholestane-1α,19-Diol 19-Acetate is a high-purity steroidal intermediate of significant importance in advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block for the development of novel steroid-based therapeutics and reference standards. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in steroid chemistry, hormone research, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and investigational drugs.
• Reference Standard: Used as a certified reference material (CRM) or analytical standard in quality control laboratories for method development, validation, and impurity profiling of steroid products.
• Biochemical Research: Employed in academic and industrial research to study steroid metabolism, enzyme interactions, and receptor binding activities.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the preparation of specialized steroidal derivatives with modified biological activity.
• Process Development: Utilized in scaling up and optimizing synthetic routes for steroid manufacturing within a GMP (Good Manufacturing Practice) environment.

Basic Information

Product Name	5α-Cholestane-1α,19-Diol 19-Acetate
CAS No.	28809-70-3
Molecular Formula	C₂₉H₅₀O₃
Molecular Weight	446.71 g/mol
Synonyms	1α,19-Dihydroxy-5α-cholestan-19-yl acetate; 19-Acetoxy-5α-cholestane-1α,19-diol; (3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-1,3,19-triol 19-acetate; 5α-Cholestane-1α,19-diol, 19-acetate; Steroid intermediate 28809-70-3
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-1α,19-Diol 19-Acetate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards, and custom purity grades or analytical packages can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storage under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.