Description

(D)-n-(Benzyloxycarbonyl)Pipecolic Acid is a protected, non-proteinogenic amino acid derivative of significant importance in advanced organic synthesis. This high-purity chiral building block is critical for researchers and manufacturers requiring precise stereochemistry in their final products. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel active pharmaceutical ingredients (APIs), peptide-based therapeutics, and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, enzyme modulators, and other bioactive molecules.
• Peptide Chemistry: Used for the controlled incorporation of the (D)-pipecolic acid moiety into custom peptides and peptidomimetics.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Asymmetric Synthesis: Employed in the preparation of complex natural products and chiral catalysts due to its defined stereocenter.
• Bioconjugation: Can be used in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic platforms.

Basic Information

Product Name	(D)-n-(Benzyloxycarbonyl)Pipecolic Acid
CAS No.	28697-09-8
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	(D)-N-Cbz-Pipecolic Acid; (D)-1-[(Benzyloxy)carbonyl]piperidine-2-carboxylic Acid; (2R)-1-[(Phenylmethoxy)carbonyl]piperidine-2-carboxylic Acid; (R)-1-Cbz-Pipecolic Acid; (R)-N-Carbobenzyloxy-pipecolic Acid; (D)-N-Carbobenzyloxy-2-piperidinecarboxylic Acid; (R)-N-Cbz-2-piperidinecarboxylic Acid; (R)-1-[(Benzyloxy)carbonyl]piperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our (D)-n-(Benzyloxycarbonyl)Pipecolic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.