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3Beta,12Beta,14-Trihydroxy-5Beta-Card-20(22)-Enolide, Monodigitoxoside CAS NO 28553-21-1
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CAS No.:28553-21-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3Beta,12Beta,14-Trihydroxy-5Beta-Card-20(22)-Enolide, Monodigitoxoside is a high-purity cardiac glycoside derivative, specifically a monodigitoxoside of a cardenolide structure. This compound is of significant interest in pharmaceutical research and development due to its potential biological activity related to cardiac function. It serves as a critical reference standard and a key pharmaceutical intermediate for researchers and manufacturers in the life sciences sector. Target industries include pharmaceutical R&D, biotechnology, and fine chemical synthesis.
Application
- Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of cardiac glycosides in research and quality control laboratories.
- Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of novel or generic cardiac therapeutic agents.
- Biochemical Research: Employed in studies investigating the mechanism of action, structure-activity relationships (SAR), and metabolism of cardenolides.
- Analytical Method Development: Critical for developing and validating chromatographic methods (e.g., HPLC, LC-MS) for cardiac glycoside detection.
- Pharmacology Studies: Used in in vitro and in vivo assays to evaluate potency, efficacy, and toxicity profiles.
Basic Information
| Product Name | 3Beta,12Beta,14-Trihydroxy-5Beta-Card-20(22)-Enolide, Monodigitoxoside |
| CAS No. | 28553-21-1 |
| Molecular Formula | C₂₉H₄₄O₁₀ |
| Molecular Weight | 540.66 g/mol |
| Synonyms | Digitoxigenin monodigitoxoside; 3β,12β,14-Trihydroxy-5β-card-20(22)-enolide 3-β-D-digitoxoside; 12β-Hydroxydigitoxigenin monodigitoxoside; 12β-Hydroxydigitoxin; 12-Hydroxydigitoxigenin β-D-digitoxoside; Card-20(22)-enolide, 3,12,14-trihydroxy-, (3β,5β,12β)-, monodigitoxoside; 28553-21-1; 3β,12β,14-Trihydroxy-5β,14β-card-20(22)-enolide 3-(6-deoxy-β-D-galactopyranoside) |
| EINECS | Contact for details |
Quality Control
Our 3Beta,12Beta,14-Trihydroxy-5Beta-Card-20(22)-Enolide, Monodigitoxoside is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every lot to guarantee traceability and consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
| Specific Optical Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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