Description

5-Chloro-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-4-Hydroxy-2-Methoxybenzamide Monohydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the synthesis and development of active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, particularly for neurological and psychiatric applications.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process chemistry for developing new drug candidates.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry & Scale-Up: Utilized in route scouting, optimization, and pilot-scale manufacturing of complex molecules.
• Biochemical Research: Investigated for its interaction with biological targets in pharmacological studies.

Basic Information

Product Name	5-Chloro-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-4-Hydroxy-2-Methoxybenzamide Monohydrochloride
CAS No.	28478-48-0
Molecular Formula	C₁₆H₂₄Cl₂N₂O₃
Molecular Weight	363.28 g/mol
Synonyms	5-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-4-hydroxy-2-methoxybenzamide hydrochloride; 5-Chloro-4-hydroxy-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide monohydrochloride; Benzamide, 5-chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-4-hydroxy-2-methoxy-, monohydrochloride; L-741,626 hydrochloride; L741626 hydrochloride; (S)-5-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-4-hydroxy-2-methoxybenzamide hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-4-Hydroxy-2-Methoxybenzamide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and identification by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.