Description

2-Amino-5-Methylbenzene-1-Carbohydrazide is a specialized aromatic carbohydrazide derivative that serves as a versatile intermediate in advanced organic synthesis. Its unique structure, featuring both amino and hydrazide functional groups, makes it a valuable precursor for constructing complex heterocyclic systems and fine chemicals. This compound is primarily utilized by research and development laboratories, as well as production facilities in the pharmaceutical and agrochemical sectors, for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those with heterocyclic cores like pyrazoles, triazoles, and other nitrogen-containing bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, where its amino group is essential for diazotization and coupling reactions.
• Coordination Chemistry & Ligand Synthesis: Acts as a chelating ligand or precursor for ligands in metal-organic frameworks (MOFs) and catalysts due to its multiple donor atoms (N, O).
• Polymer Chemistry: Employed in the synthesis of specialty polymers, including polyhydrazides and polyamides, where it can impart specific thermal or mechanical properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating libraries of novel chemical entities for screening.

Basic Information

Product Name	2-Amino-5-Methylbenzene-1-Carbohydrazide
CAS No.	28461-49-6
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	2-Amino-5-methylbenzhydrazide; 2-Amino-5-methylbenzohydrazide; 2-Amino-5-methyl-1-carbohydrazidebenzene; 5-Methylanthranilic acid hydrazide; 2-Carbohydrazido-4-methylaniline; (2-Amino-5-methylphenyl)carbohydrazide; 4-Methyl-2-aminobenzhydrazide; 2-Amino-5-methylbenzoylhydrazine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methylbenzene-1-Carbohydrazide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), identification (IR), and impurity profiles. Our quality systems are designed to support cGMP requirements for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. For long-term storage, consider using an inert atmosphere to mitigate potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Single impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.