Description

(3-Hydroxy-Benzyl)-Carbamic Acid tert-Butyl Ester is a protected amine derivative, specifically a carbamate, that serves as a crucial building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate, where the tert-butyloxycarbonyl (Boc) protecting group safeguards the amine functionality during multi-step reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals. Its specific structure makes it integral for constructing complex molecules requiring selective deprotection and further functionalization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development and production of novel pesticides and herbicides.
• Peptide Synthesis: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide chemistry.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing heterocycles and other sophisticated organic frameworks.
• Chemical Biology Probes: Utilized in the creation of molecular probes and labeled compounds for biological studies.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of specialized polymers.

Basic Information

Product Name	(3-Hydroxy-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	28387-66-8
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	3-(Boc-amino)benzyl alcohol; N-Boc-3-aminobenzyl alcohol; tert-Butyl (3-hydroxybenzyl)carbamate; N-(tert-Butoxycarbonyl)-3-aminobenzyl alcohol; (3-Aminobenzyl)carbamic acid tert-butyl ester; Boc-3-aminobenzyl alcohol; 3-((tert-Butoxycarbonyl)amino)benzenemethanol; 3-Hydroxybenzylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (3-Hydroxy-Benzyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.