Description

L-α-Methylphenylalanine is a non-natural, chiral amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its value lies in its role as a key chiral building block for the preparation of peptide mimetics, enzyme inhibitors, and other bioactive compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce steric and electronic modifications into peptide backbones.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel protease inhibitors, receptor agonists/antagonists, and other therapeutic peptides.
• Peptidomimetics Research: Used to synthesize constrained peptide analogs with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective catalytic reactions.
• Agrochemical Development: A potential building block for creating chiral active ingredients with specific biological activity.
• Biochemical Tool: Employed in studying enzyme-substrate interactions and designing mechanism-based inhibitors.
• Fine Chemical Synthesis: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	L-α-Methylphenylalanine
CAS No.	28385-43-5
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(S)-2-Amino-2-methyl-3-phenylpropanoic acid; (S)-α-Methylphenylalanine; L-α-Methylphenylalanine; L-2-Amino-2-methyl-3-phenylpropionic acid; (S)-2-Methyl-2-aminocinnamic acid; H-α-Me-Phe-OH; (S)-2-Methylphenylalanine
EINECS	Contact for details

Quality Control

Our L-α-Methylphenylalanine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, and NMR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.