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Quinidine Polygalacturonate CAS NO 28371-10-0
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CAS No.:28371-10-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Quinidine Polygalacturonate is a pharmaceutical-grade salt formed from the alkaloid quinidine and polygalacturonic acid. This compound is valued for its specific pharmacological activity, primarily as an antiarrhythmic agent, and offers a distinct profile compared to other quinidine salts. It is essential for manufacturers in the pharmaceutical industry developing cardiac medications, as well as for research institutions conducting studies on ion channel function and cardiac electrophysiology.
Application
- Pharmaceutical Active Ingredient (API): Primary use as the active component in formulated antiarrhythmic medications for the treatment of cardiac arrhythmias.
- Cardiac Research: A critical reference standard and tool in preclinical and clinical research for studying myocardial conduction and sodium channel blockade.
- Drug Formulation Development: Used in the development of various dosage forms, including tablets and capsules, where its specific salt form can influence stability and bioavailability.
- Biochemical Standard: Serves as a high-purity standard in analytical laboratories for quality control and method validation of quinidine-based products.
- Veterinary Medicine: Potential application in veterinary cardiology for managing similar cardiac conditions in animals.
Basic Information
| Product Name | Quinidine Polygalacturonate |
| CAS No. | 28371-10-0 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | Quinidine Polygalacturonate; Quinidine Pectinate; Cinchonan-9-ol, 6'-methoxy-, (9S)-, polymer with α-D-galactopyranuronic acid; Quinidine Galacturonate; Quinidine Pectin; Quinidine Polymannuronate (related); Quinidine Alginate (related); Antiarrhythmic Agent |
| EINECS | Contact for details |
Quality Control
Our Quinidine Polygalacturonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmaceutical industry standards. A detailed Certificate of Analysis (COA) providing batch-specific results is available for review and regulatory submission.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference standard |
| Assay (HPLC) | 98.0% - 102.0% (on anhydrous basis) |
| Water (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
| Related Substances (HPLC) | Individual impurity ≤ 0.5%; Total impurities ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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