Description

n-Hydroxyadamantane-1-Carboxamide is a high-purity, functionalized adamantane derivative of significant interest in advanced organic synthesis. This compound matters for its role as a versatile building block and intermediate in the development of novel pharmaceutical agents and specialty materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the rigid, lipophilic adamantane scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in antiviral, neurological, and anti-inflammatory research.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its unique three-dimensional structure.
• Material Science Research: Serves as a precursor for novel polymers, coatings, or supramolecular assemblies that benefit from the adamantane moiety's thermal stability and hydrophobicity.
• Agrochemical Development: Investigated as an intermediate in the synthesis of novel crop protection agents with potentially enhanced efficacy and environmental profiles.
• Catalyst Ligand Precursor: The functional groups can be modified to create novel ligands for catalytic systems in asymmetric synthesis.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in related API manufacturing.

Basic Information

Product Name	n-Hydroxyadamantane-1-Carboxamide
CAS No.	28309-44-6
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	1-Adamantanecarbohydroxamic Acid; 1-Hydroxycarbamoyladamantane; Adamantane-1-carbohydroxamic Acid; 1-Carbamoyloxyadamantane; N-Hydroxy-1-adamantanecarboxamide; 1-Adamantylhydroxamic Acid; 1-(Hydroxycarbamoyl)adamantane; NSC 163063
EINECS	Contact for details

Quality Control

Our n-Hydroxyadamantane-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.