Description

o-sec-Butyl-Alpha,Alpha,Beta,β-Tetrafluorophenetole CAS NO 28202-34-8 is a specialized fluorinated aromatic ether compound, serving as a valuable intermediate in advanced organic synthesis. Its molecular structure, featuring a tetrafluorinated phenyl ring and a sec-butoxy side chain, makes it a critical precursor for developing high-performance materials and active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise fluorination patterns are required to modulate biological activity and material properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where fluorination enhances stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorine atoms into polymer backbones, enhancing chemical resistance and surface properties of high-performance plastics.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions and nucleophilic aromatic substitution for introducing complex ether functionalities.
• Research & Development: Critical for academic and industrial R&D exploring structure-activity relationships (SAR) in fluorinated compounds.

Basic Information

Product Name	o-sec-Butyl-Alpha,Alpha,Beta,β-Tetrafluorophenetole
CAS No.	28202-34-8
Molecular Formula	C12H14F4O
Molecular Weight	250.23 g/mol
Synonyms	1-(sec-Butoxy)-2,3,5,6-tetrafluorobenzene; 2,3,5,6-Tetrafluoro-1-(sec-butoxy)benzene; o-sec-Butoxytetrafluorobenzene; Benzene, 1-(1-methylpropoxy)-2,3,5,6-tetrafluoro-; 2,3,5,6-Tetrafluorophenyl sec-butyl ether; Tetrafluorophenetole, o-sec-butyl-; α,α,β,β-Tetrafluoro-o-sec-butoxyphenetole
EINECS	Contact for details

Quality Control

Our production of o-sec-Butyl-Alpha,Alpha,Beta,β-Tetrafluorophenetole adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for fine chemical and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (by GC/HPLC), identity confirmation (by FT-IR, NMR), and impurity profiles. We operate under a cGMP-compliant quality system to ensure traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.