Description

3-Cyanobenzyl Bromide is a versatile and high-purity organic building block essential for advanced chemical synthesis. Its reactive benzyl bromide and cyano functional groups make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzyl or arylacetic acid motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organic transformations.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Peptide Modification: Useful for introducing functionalized benzyl groups into peptides and other biomolecules.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination.

Basic Information

Product Name	3-Cyanobenzyl Bromide
CAS No.	28188-41-2
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	m-Cyanobenzyl Bromide; 3-(Bromomethyl)benzonitrile; α-Bromo-m-tolunitrile; (3-Cyanophenyl)methyl Bromide; m-Tolunitrile, α-bromo-; Benzonitrile, 3-(bromomethyl)-; 1-Bromomethyl-3-cyanobenzene
EINECS	Contact for details

Quality Control

Our 3-Cyanobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.