Description

2-Hydroxyisophthalonitrile is a versatile aromatic nitrile derivative with a phenolic hydroxyl group, serving as a key synthetic intermediate in advanced organic chemistry. Its bifunctional nature makes it a valuable precursor for constructing complex heterocyclic systems and functional polymers. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those with heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Resin Precursor: Serves as a monomer or cross-linking agent for high-temperature and specialty engineering plastics.
• Dye & Pigment Manufacturing: An intermediate in the synthesis of complex organic colorants and photostable pigments.
• Ligand & Chelating Agent Synthesis: Used to create functional ligands for catalysis and metal ion complexation.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Hydroxyisophthalonitrile
CAS No.	28177-80-2
Molecular Formula	C8H4N2O
Molecular Weight	144.13 g/mol
Synonyms	2-Hydroxybenzene-1,3-dicarbonitrile; 1,3-Dicyano-2-hydroxybenzene; Isophthalonitrile, 2-hydroxy-; 2-Cyanophenol-3-carbonitrile; 2-Hydroxy-1,3-dicyanobenzene; 2-Hydroxy-m-phthalonitrile
EINECS	Contact for details

Quality Control

Our 2-Hydroxyisophthalonitrile is produced and tested under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters such as assay (HPLC), moisture content, and related substances. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.