Description

2-Hydroxy-3-Iodobenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical synthetic intermediate. Its molecular structure, featuring both a phenolic hydroxyl group and an iodine substituent, makes it a valuable building block for constructing complex molecules in advanced chemical synthesis. This compound is essential for research and development chemists and production units in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific functional groups or create novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the iodine moiety can be leveraged for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications due to the reactivity of the iodine atom.
• Custom Synthesis and Contract Manufacturing: A high-purity building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Hydroxy-3-Iodobenzonitrile
CAS No.	28177-77-7
Molecular Formula	C7H4INO
Molecular Weight	244.02 g/mol
Synonyms	3-Iodo-2-hydroxybenzonitrile; 2-Cyano-6-iodophenol; 6-Iodo-2-hydroxybenzonitrile; 2-Hydroxy-3-iodobenzonitrile; Benzonitrile, 2-hydroxy-3-iodo-; 3-Iodosalicylonitrile; Salicylonitrile, 3-iodo-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure to light during handling and storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.