Description

2-Chloro-4-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of its functional groups, which enable precise chemical transformations for creating complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with heterocyclic or substituted aromatic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging the reactivity of the nitro and cyano groups.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating azo dyes and other complex colorants.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and other functional layers in electronic materials.
• Liquid Crystal (LC) Materials: Used in the synthesis of compounds for display technologies.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki and Buchwald-Hartwig amination for constructing biaryl systems.
• Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Chloro-4-Nitrobenzonitrile
CAS No.	28163-00-0
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	2-Chloro-4-nitrobenzenecarbonitrile; 4-Nitro-2-chlorobenzonitrile; Benzonitrile, 2-chloro-4-nitro-; 2-Chloro-4-cyanomitrobenzene; 2-Chloro-4-nitro-phenyl cyanide; NSC 403119; 2-Cl-4-NO2-Benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Nitrobenzonitrile is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.