Description

8-Fluoroguanine is a fluorinated purine derivative, a key building block in medicinal chemistry and life science research. Its primary value lies in its role as a versatile intermediate for synthesizing novel nucleoside analogs and potential pharmaceutical agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors, particularly those developing antiviral or anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs with potential antiviral and anticancer activities.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate purine metabolism and related pathways.
• Antiviral Drug Development: Serves as a building block for prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Agrochemical Research: Employed in the discovery and development of novel pesticides and plant growth regulators.
• Diagnostic Probe Synthesis: Utilized to create labeled compounds for molecular imaging and diagnostic assays.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring novel chemical entities and structure-activity relationships (SAR).

Basic Information

Product Name	8-Fluoroguanine
CAS No.	28128-36-1
Molecular Formula	C5H4FN5O
Molecular Weight	169.12 g/mol
Synonyms	8-Fluoroguanine; 8-Fluoro-1H-purin-6-amine; 8-Fluoro-9H-purin-6-amine; 8-Fluoroguanine; Guanin, 8-fluoro-; 8-Fluoroguanine (8-FG); 8-Fluoro-6-aminopurine; 8-Fluoro-6-aminopurine
EINECS	Contact for details

Quality Control

Our 8-Fluoroguanine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.