Description

n-Acetyltyramine Glucuronide is a high-purity biochemical conjugate of tyramine, a biogenic amine, and glucuronic acid. This compound is of significant value as a key metabolite and analytical reference standard in pharmaceutical and life science research. It is primarily required by researchers and manufacturers in the fields of drug metabolism studies, biomarker discovery, and clinical diagnostics for the accurate quantification and understanding of metabolic pathways.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification of tyramine metabolites in bioanalytical assays.
• Drug Metabolism and Pharmacokinetics (DMPK): Critical for studying Phase II conjugation pathways, specifically glucuronidation, in preclinical and clinical research.
• Biomarker Research: Serves as a target analyte in the development of diagnostic methods for conditions related to neurotransmitter and dietary amine metabolism.
• Enzyme Activity Assays: Employed as a substrate to study the activity and kinetics of UDP-glucuronosyltransferase (UGT) enzymes.
• Toxicology Studies: Used in investigations of detoxification pathways and the metabolic fate of aromatic amines.
• Academic Research: A vital tool in biochemistry and molecular biology laboratories for fundamental research on conjugation reactions.

Basic Information

Product Name	n-Acetyltyramine Glucuronide
CAS No.	28116-26-9
Molecular Formula	C17H21NO9
Molecular Weight	383.35 g/mol
Synonyms	N-Acetyltyramine Glucuronide; 4-[2-(Acetylamino)ethyl]phenyl β-D-Glucopyranosiduronic Acid; Tyramine Glucuronide, N-Acetyl-; N-Acetyl-4-(2-aminoethyl)phenyl β-D-glucopyranosiduronic acid; Acetyltyramine Glucuronide; 28116-26-9; N-Acetyl tyramine glucuronide
EINECS	Contact for details

Quality Control

Our n-Acetyltyramine Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.