Description

2-Pyrrolidinemethanol, 1-Acetyl-5-Methyl-, trans- (8Ci) CAS NO 28115-46-0 is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the construction of complex molecules with precise three-dimensional architecture. Pharmaceutical research and development teams, particularly those focused on central nervous system (CNS) agents and other bioactive nitrogen-containing compounds, are the primary industrial users seeking this material for its synthetic utility.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for neurological targets.
• Asymmetric Synthesis: Employed as a building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and process development.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in stereoselective transformations.
• Agrochemical Research: Used in the synthesis of advanced, biologically active compounds for crop protection research.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Pyrrolidinemethanol, 1-Acetyl-5-Methyl-, trans- (8Ci)
CAS No.	28115-46-0
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-1-Acetyl-5-methyl-2-pyrrolidinemethanol; (2R,5R)-1-Acetyl-5-methylpyrrolidine-2-methanol; (2S,5S)-1-Acetyl-5-methylpyrrolidine-2-methanol; 1-Acetyl-5-methyl-2-pyrrolidinemethanol (trans-); 5-Methyl-1-acetyl-2-pyrrolidinemethanol; 2-Pyrrolidinemethanol, 1-acetyl-5-methyl-, trans-; A chiral pyrrolidine derivative.
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinemethanol, 1-Acetyl-5-Methyl-, trans- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.