Description

1'-[3-(3-Chloro-10,11-Dihydro-5H-Dibenz(B,F)Azepin-5-Yl)Propyl][1,4'-Bipiperidine]-4'-Carboxamide Dihydrochloride is a high-purity, pharmaceutically relevant chemical intermediate and reference standard. This compound is critical for research and development in neuropharmacology, serving as a key building block or active metabolite in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) targeting central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development and manufacturing of novel psychotropic and neuroactive drugs.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (QC/QA) of related active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a tool compound in pharmacological studies to investigate receptor binding affinity, metabolic pathways, and structure-activity relationships (SAR).
• Metabolite Synthesis: Employed in the synthesis of specific metabolites for pharmacokinetic and toxicological studies during drug development.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and neuropharmacology.

Basic Information

Product Name	1'-[3-(3-Chloro-10,11-Dihydro-5H-Dibenz(B,F)Azepin-5-Yl)Propyl][1,4'-Bipiperidine]-4'-Carboxamide Dihydrochloride
CAS No.	28058-62-0
Molecular Formula	C28H38ClN5O • 2HCl
Molecular Weight	564.0 g/mol (for dihydrochloride salt)
Synonyms	1'-[3-(3-Chloro-5H-dibenzo[b,f]azepin-5-yl)propyl]-[1,4'-bipiperidine]-4'-carboxamide dihydrochloride; 4'-Carbamoyl-1'-[3-(3-chloro-5H-dibenzo[b,f]azepin-5-yl)propyl]-1,4'-bipiperidine dihydrochloride; Clocapramine Dihydrochloride Impurity/Intermediate; Desmethylclocapramine Dihydrochloride (potential metabolite); 1,4'-Bipiperidine, 1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]-4'-carboxamide, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1'-[3-(3-Chloro-10,11-Dihydro-5H-Dibenz(B,F)Azepin-5-Yl)Propyl][1,4'-Bipiperidine]-4'-Carboxamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and residual solvent analysis, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.