Description

Phenylac-Gln-Oh CAS NO 28047-15-6 is a high-purity, protected amino acid derivative, specifically N-α-phenylacetyl-L-glutamine, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive intermediate for the controlled construction of complex peptide chains and other bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel peptide-based therapeutics and fine chemical products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected glutamine derivative.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Research & Development: A valuable tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Intermediate in the manufacture of specialized fine chemicals and custom synthesis projects.

Basic Information

Product Name	Phenylac-Gln-Oh
CAS No.	28047-15-6
Molecular Formula	C₁₃H₁₆N₂O₄
Molecular Weight	264.28 g/mol
Synonyms	N-α-Phenylacetyl-L-glutamine; L-Glutamine, N2-(phenylacetyl)-; Phenylac-Gln-OH; N-Phenylacetylglycine; N-(Phenylacetyl)glutamine; (S)-2-(Phenylacetamido)pentanediamide; Fmoc-Gln-OH (Note: This is a different, common protected form); Protected L-Glutamine derivative
EINECS	Contact for details

Quality Control

Our Phenylac-Gln-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.