Description

Ac-Tyr(Me)-Oh CAS NO 28047-05-4 is a chemically modified, protected tyrosine derivative, specifically N-Acetyl-O-Methyl-L-tyrosine. This compound serves as a crucial protected amino acid building block for the synthesis of complex peptides and peptidomimetics, enabling advanced research and development. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and biochemical research institutions.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for incorporating modified tyrosine residues into peptide chains.
• Pharmaceutical Research: Used in the development of novel therapeutic peptides and drug candidates targeting various diseases.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides for diagnostic and imaging applications.
• Biochemical Studies: Employed to study enzyme-substrate interactions, receptor binding, and protein structure-function relationships.
• Peptidomimetic Design: Facilitates the creation of stable, bioavailable peptide analogs with enhanced pharmacological properties.
• Academic & Industrial R&D: A fundamental reagent in laboratories focused on organic synthesis, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Ac-Tyr(Me)-Oh
CAS No.	28047-05-4
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25 g/mol
Synonyms	N-Acetyl-O-methyl-L-tyrosine; Ac-O-Me-Tyr-OH; N-Acetyl-3-methoxy-L-tyrosine; (2S)-2-Acetamido-3-(4-methoxyphenyl)propanoic acid; L-Tyrosine, N-acetyl-, methyl ether; Acetyl-O-methyltyrosine; Fmoc-Tyr(Me)-OH precursor; Protected tyrosine derivative
EINECS	Contact for details

Quality Control

Our Ac-Tyr(Me)-Oh is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal standards and can support development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.