Description

Crotyl Glycine is a specialized amino acid derivative featuring an unsaturated crotyl side chain, offering unique reactivity and functionality. This compound serves as a versatile chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecular architectures. It is particularly valuable for research and development in the pharmaceutical, agrochemical, and specialty chemical industries, where precise structural control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in peptidomimetics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Peptide Chemistry: Serves as a non-proteinogenic amino acid analog for constructing modified peptides with enhanced stability or biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Bioconjugation and Linker Chemistry: The reactive double bond makes it useful for creating chemical linkers in bioconjugation and prodrug strategies.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Crotyl Glycine
CAS No.	28024-56-8
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(E)-2-Amino-4-hexenoic Acid; (E)-2-Aminohex-4-enoic Acid; trans-2-Amino-4-hexenoic Acid; Crotylglycine; 4-Hexenoic acid, 2-amino-, (E)-; 2-Amino-4-hexenoic acid (E)-; (E)-Crotylglycine; DL-Crotylglycine
EINECS	Contact for details

Quality Control

Our Crotyl Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and isomer content analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (E/Z ratio)	≥ 95:5 (E-isomer)
Optical Purity (Chiral HPLC)	Specify (DL, D, or L)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.