Description

A-Naphthoic Acid-Carboxy-14C is a carbon-14 radiolabeled derivative of 1-naphthoic acid, a key aromatic carboxylic acid. This isotopically labeled compound is essential for precise metabolic and environmental fate studies, providing critical data for regulatory submissions and scientific research. It is primarily utilized by researchers and quality control professionals in the pharmaceutical, agrochemical, and environmental science industries for advanced analytical applications.

Application

• Tracer Studies in Metabolism Research: Used to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of pharmaceutical compounds and agrochemicals.
• Environmental Fate and Degradation Analysis: Employed to trace the breakdown pathways, persistence, and mobility of chemical substances in soil and water systems.
• Biochemical Pathway Elucidation: Serves as a tool to study specific enzymatic reactions and metabolic pathways in biological systems.
• Drug Development and Safety Assessment: Critical for conducting radiolabeled mass balance studies required for regulatory filings with agencies like the FDA and EMA.
• Analytical Method Development and Validation: Acts as an internal standard or reference material in advanced chromatographic techniques such as LC-MS.
• Material Science Research: Can be used in studies investigating the synthesis and properties of novel labeled polymers or organic materials.

Basic Information

Product Name	A-Naphthoic Acid-Carboxy-14C
CAS No.	27971-51-3
Molecular Formula	C11H814CO2H
Molecular Weight	~188.19 (based on 12C form)
Synonyms	1-Naphthoic Acid-1-14C; 1-Naphthalenecarboxylic Acid-1-14C; 1-Carboxynaphthalene-1-14C; α-Naphthoic Acid-1-14C; NSC 7655-14C; [1-14C]-1-Naphthoic Acid; [carboxy-14C]-1-Naphthoic Acid
EINECS	Contact for details

Quality Control

Every batch of A-Naphthoic Acid-Carboxy-14C is manufactured and analyzed under strict quality protocols to ensure identity, purity, and specific activity. Our quality assurance includes comprehensive analytical testing via HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting radiopurity (typically >98%), chemical purity, and specific activity. We adhere to cGMP principles for the production of labeled compounds intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures between 2°C and 8°C (refrigerated) or as specified on the label. For long-term storage, keep at or below -20°C. The product is light-sensitive and should be handled in accordance with standard laboratory safety procedures for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity	≥ 98%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (if supplied as solution)	Specified on COA (e.g., Ethanol, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.