Description

(14β,17α)-3β,19-Diacetoxy-5,14-Dihydroxy-21-(Iodoacetoxy)-5β-Pregnan-20-One CAS NO 27953-46-4 is a high-purity, multi-functional steroid derivative characterized by its specific acetoxy and iodoacetoxy functional groups. This compound is a critical advanced pharmaceutical intermediate for the synthesis of complex steroid-based active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of specialized corticosteroids and other bioactive steroid molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Biochemical Probe: Serves as a tool compound in biochemical research due to its reactive iodoacetoxy group, which can be used for alkylation studies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for complex steroid derivatives in pilot plants.

Basic Information

Product Name	(14β,17α)-3β,19-Diacetoxy-5,14-Dihydroxy-21-(Iodoacetoxy)-5β-Pregnan-20-One
CAS No.	27953-46-4
Molecular Formula	C₂₈H₃₉IO₉
Molecular Weight	646.51 g/mol
Synonyms	21-(Iodoacetoxy)-3β,19-diacetoxy-5β,14β,17α-pregnan-5,14,20-trione; 3β,19-Diacetoxy-5,14-dihydroxy-21-(iodoacetoxy)-5β-pregnan-20-one; 5β-Pregnan-20-one, 3β,19-diacetoxy-5,14-dihydroxy-21-(iodoacetoxy)-, (14β,17α)-; Iodoacetoxy Pregnane Derivative; Steroid Iodoacetate Intermediate
EINECS	Contact for details

Quality Control

Our (14β,17α)-3β,19-Diacetoxy-5,14-Dihydroxy-21-(Iodoacetoxy)-5β-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting specifications for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.