Description

(R)-3-Methylpyrrolidin-2-One CAS NO 27948-40-9 is a high-purity, chiral lactam building block essential for the synthesis of complex pharmaceutical intermediates and fine chemicals. Its defined stereochemistry provides a critical advantage in creating enantiomerically pure compounds, ensuring high efficacy and reducing unwanted side effects in final drug products. This material is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular drugs.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for metal-catalyzed asymmetric reactions, enhancing stereoselectivity.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific chiral configurations.
• Academic & Industrial Research: A valuable reagent for medicinal chemistry research and process development in organic synthesis.
• Polymer Modification: Can be used to introduce chiral centers into polymer backbones for advanced material properties.

Basic Information

Product Name	(R)-3-Methylpyrrolidin-2-One
CAS No.	27948-40-9
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	(R)-3-Methyl-2-pyrrolidinone; (R)-3-Methylpyrrolidinone; (R)-3-Methyl-2-pyrrolidone; (R)-3-Methylbutyrolactam; (R)-N-Methyl-γ-butyrolactam; (3R)-3-Methylpyrrolidin-2-one; (R)-(-)-3-Methyl-2-pyrrolidinone; (R)-3-Methyl-2-oxopyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-3-Methylpyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.