Description

5-Hydroxy Tryptophol β-D-Glucuronide is a specific glucuronide conjugate of the serotonin metabolite 5-hydroxytryptophol. This compound is of significant value in biochemical research and analytical method development, particularly for studying serotonin metabolism and glucuronidation pathways. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors.

Application

• Biochemical Research Standard: Used as a high-purity reference material for studying serotonin (5-HT) metabolic pathways and glucuronidation kinetics.
• Diagnostic Reagent Development: Serves as a key intermediate or calibrant in the development of clinical diagnostic assays for neurotransmitter metabolites.
• Pharmaceutical Intermediate: Acts as a specialized building block or metabolite standard in the research and development of neuroactive pharmaceuticals.
• Metabolite Analysis: Essential for the quantification and validation of 5-hydroxytryptophol glucuronide in biological samples via LC-MS or HPLC.
• Enzymology Studies: Employed as a substrate to study the activity and specificity of UDP-glucuronosyltransferase (UGT) enzymes.
• Toxicology & Biomarker Research: Used in investigations related to neurotransmitter imbalance, alcohol consumption biomarkers, and related toxicological studies.

Basic Information

Product Name	5-Hydroxy Tryptophol β-D-Glucuronide
CAS No.	27939-38-4
Molecular Formula	C₁₇H₂₁NO₉
Molecular Weight	383.35 g/mol
Synonyms	5-Hydroxytryptophol Glucuronide; 5-HTOL-Gluc; 5-Hydroxyindole-3-ethanol β-D-glucopyranosiduronic acid; (2S,3S,4S,5R,6S)-6-((1S)-1-Hydroxy-2-(5-hydroxy-1H-indol-3-yl)ethoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid; 5-Hydroxytryptophol β-D-Glucopyranosiduronic Acid; Serotonin Metabolite Glucuronide; 5-HTOL-Glucuronide
EINECS	Contact for details

Quality Control

Our 5-Hydroxy Tryptophol β-D-Glucuronide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.