Description

[6R-(6Alpha,7Beta)]-3-(Acetoxymethyl)-7-(Hydroxyphenylacetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key chemical intermediate in the synthesis of advanced pharmaceutical compounds. This compound is of critical importance for its role as a precursor in the production of specific cephalosporin antibiotics, enabling precise control over the final drug's structure and efficacy. It is primarily required by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of cephalosporin-class antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key starting material or intermediate in the research and production of novel antibacterial agents.
• Biochemical Research: Used in laboratory studies to investigate structure-activity relationships (SAR) and mechanisms of action for β-lactam compounds.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecules with specific stereochemistry.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.

Basic Information

Product Name	[6R-(6Alpha,7Beta)]-3-(Acetoxymethyl)-7-(Hydroxyphenylacetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	27910-26-5
Molecular Formula	C20H20N2O7S
Molecular Weight	432.45 g/mol
Synonyms	7-(2-Hydroxyphenylacetamido)-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-7-[(2-Hydroxyphenyl)acetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin C derivative intermediate; 3-Acetoxymethyl-7-(2-hydroxyphenylacetamido)ceph-3-em-4-carboxylic acid; 7-ADCA derivative; 7-[(2-Hydroxyphenylacetyl)amino]cephalosporanic acid derivative
EINECS	Contact for details

Quality Control

Our [6R-(6Alpha,7Beta)]-3-(Acetoxymethyl)-7-(Hydroxyphenylacetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters are available upon request. We support compliance with cGMP and relevant pharmacopeial guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.