Description

4-Nitrophenyl4-o-(2,3,4,6-Tetra-o-Acetyl-B-D-Galactopyranosyl)-2,3,6-Tri-o-Acetyl-B-D-Thioglucopyranoside is a sophisticated, fully acetylated thioglycoside derivative, serving as a critical synthetic intermediate and biochemical tool. This compound is valued for its role in the controlled synthesis and study of complex oligosaccharides and glycoconjugates. It is primarily utilized by researchers and manufacturers in pharmaceutical development, carbohydrate chemistry, and enzymology, particularly for investigating glycosidase enzymes and developing novel glycotherapeutics.

Application

• Glycosidase Substrate & Inhibitor Development: Acts as a chromogenic or synthetic precursor for substrates used to assay the activity of β-galactosidases and related enzymes.
• Oligosaccharide & Glycoconjugate Synthesis: Serves as a key building block (glycosyl donor) in the chemical and enzymatic synthesis of complex carbohydrate structures.
• Pharmaceutical Research: Used in the discovery and development of glycosidase-targeted drugs for conditions like lysosomal storage disorders, diabetes, and viral infections.
• Biochemical Probe: Employed in mechanistic studies to understand glycosyl transfer reactions and enzyme specificity.
• Diagnostic Reagent Manufacturing: A precursor for synthesizing reagents used in clinical diagnostic kits for enzyme deficiency detection.
• Glycobiology Research: Essential for academic and industrial research focused on carbohydrate-protein interactions and cell surface recognition processes.

Basic Information

Product Name	4-Nitrophenyl4-o-(2,3,4,6-Tetra-o-Acetyl-B-D-Galactopyranosyl)-2,3,6-Tri-o-Acetyl-B-D-Thioglucopyranoside
CAS No.	27894-81-1
Molecular Formula	C₃₄H₄₃NO₂₀S
Molecular Weight	841.77 g/mol
Synonyms	p-Nitrophenyl 4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-2,3,6-tri-O-acetyl-β-D-thioglucopyranoside; 4-Nitrophenyl β-D-thiogalactopyranosyl-(1→4)-β-D-thioglucopyranoside heptaacetate; PNPGalβ(1-4)Glcβ-SPhNO2 heptaacetate; Hepta-O-acetyl-4-nitrophenyl β-lactosyl thioglycoside; 4-Nitrophenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-1-thio-β-D-glucopyranoside; Lactosyl donor analog; Thioglycoside enzyme substrate precursor.
EINECS	Contact for details

Quality Control

Our production of this advanced biochemical intermediate adheres to stringent quality protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm structural identity and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and spectroscopic data. Our quality management system supports compliance with research and cGMP-grade material requirements for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive); containers should be allowed to equilibrate to room temperature before opening to prevent condensation. Store in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.