Description

3B,11B,21-Trihydroxy-5B-Pregnan-20-One is a high-purity steroid derivative and a key intermediate in organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for the development of more complex molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for use in steroid synthesis and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in metabolic studies and enzyme inhibition assays.
• Fine Chemical Synthesis: Serves as a chiral building block for constructing complex organic molecules with specific biological activity.
• Hormone Analog Development: Employed in research and development for creating novel corticosteroid or other hormonal analogs.

Basic Information

Product Name	3B,11B,21-Trihydroxy-5B-Pregnan-20-One
CAS No.	27857-26-7
Molecular Formula	C21H34O4
Molecular Weight	350.49 g/mol
Synonyms	5β-Pregnan-3β,11β,21-triol-20-one; 3β,11β,21-Trihydroxy-5β-pregnan-20-one; 11β,21-Dihydroxy-3β-hydroxy-5β-pregnan-20-one; 5β-Pregnan-20-one, 3β,11β,21-trihydroxy-; Tetrahydrocorticosterone; 5β-Tetrahydrocorticosterone; 3β,11β,21-Trihydroxy-5β-pregnane-20-one
EINECS	Contact for details

Quality Control

Our 3B,11B,21-Trihydroxy-5B-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.