Description

2,2,2-Trifluoro-1-Methylethyl Cyanoacetate is a high-value fluorinated building block and specialty ester. This compound is critical for introducing the trifluoroethoxy moiety into complex molecules, enabling the fine-tuning of physicochemical properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where the trifluoroethoxy group can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing properties like chemical resistance, hydrophobicity, and optical clarity.
• Organic Synthesis Reagent: Acts as a versatile reagent in Knoevenagel condensations and other C-C bond-forming reactions to create α-cyanoacrylates and other complex esters.
• Dye & Pigment Intermediate: Utilized in the production of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2,2,2-Trifluoro-1-Methylethyl Cyanoacetate
CAS No.	27827-87-8
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	2,2,2-Trifluoroethyl Cyanoacetate; 1,1,1-Trifluoro-2-propyl Cyanoacetate; 2-Cyanoacetic Acid 2,2,2-Trifluoro-1-Methylethyl Ester; Trifluoroethyl Cyanoacetate; 2,2,2-Trifluoro-1-methylethyl 2-cyanoacetate; (2,2,2-Trifluoro-1-methylethoxy)carbonylacetonitrile; 2,2,2-Trifluoroethyl 2-cyanoacetate; Cyanoacetic Acid Trifluoroethyl Ester
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Methylethyl Cyanoacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.