Description

2-Chloropropionamide is a versatile halogenated amide intermediate with significant utility in organic synthesis. Its reactive chloro and amide functional groups make it a valuable building block for constructing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, fine chemicals, and specialty polymers who require a reliable, high-purity synthetic precursor.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various active pharmaceutical ingredients (APIs), including potential antiviral and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where the chloropropionamide moiety is a critical structural component.
• Organic Synthesis Reagent: Serves as a versatile electrophile in nucleophilic substitution reactions and as a precursor for heterocyclic compounds like oxazolines and thiazoles.
• Polymer Chemistry: Acts as a monomer or co-monomer in the production of specialty polyamides and other functional polymers.
• Bioconjugation & Protein Modification: Utilized in research for modifying peptides and proteins due to its reactive halogen site.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-Chloropropionamide
CAS No.	27816-36-0
Molecular Formula	C3H6ClNO
Molecular Weight	107.54 g/mol
Synonyms	2-Chloropropanamide; α-Chloropropionamide; Propionamide, 2-chloro-; NSC 403697; 2-Chloro-propanamide; Chloropropionamide; 2-Chloropropionic acid amide
EINECS	Contact for details

Quality Control

Our 2-Chloropropionamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.